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Yasuo Kurimoto, MD, PhD

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Expertises:

Glaucoma, Retina, Regenerative Medicine

Current Affiliation:

Director, Kobe City Eye Hospital

Publications

  1. Sakai D, Hirami Y, Yokota S, Onishi A, Takahashi M, Nakamura M, Kurimoto Y, Maeda A: Deep phenotyping of eyes shut homolog-associated retinopathy based on visual impairment patterns. Front Ophthalmol 5:1672451, 2025.

  2. Igarashi S, Mandai M, Totani K, Yamanari M, Sakai D, Yamamoto M, Hirami Y, Sugiyama S, Kurimoto Y: Characterization of the depolarization contrast line in the outer retina using polarization-sensitive optical coherence tomography. Sci Rep 15:25394, 2025.

  3. Sakai D, Mandai M, Hirami Y, Yamamoto M, Ito SI, Igarashi S, Yokota S, Uyama H, Fujihara M, Maeda A, Terada M, Nishida M, Shibata Y, Hayashi N, Iseki K, Miura T, Kajita K, Ishida M, Sugita S, Maeda T, Takahashi M, Kurimoto Y: Transplant of induced pluripotent stem cell-derived retinal pigment epithelium strips for macular degeneration and retinitis pigmentosa. Ophthalmol Sci 5(4):100770, 2025.

  4. Ozaki A, Sugita S, Ishida M, Nishida M, Iseki K, Sakai N, Hayashi N, Shiina T, Yokota S, Ito S, Fujihara M, Kondo M, Takahashi M, Kurimoto Y, Mandai M: Allogenic transplantation of RPE strips lacking MHC class II can avoid rejection in nonhuman primate eyes. Invest Ophthalmol Vis Sci 66(6):53, 2025.

  5. Igarashi S, Matsuzaki M, Hirota M, Miyazaki W, Yamamoto S, Yoshimizu S, Uyama H, Yokota S, Fujihara M, Hirose F, Kurimoto Y: Utility of intraoperative optical coherence tomography in filtration surgery using MicroShunt. Jpn J Ophthalmol 69(3):425-431, 2025.

  6. Ito SI, Nakamura T, Sakai D, Hirota M, Sotozono C, Kurimoto Y: Nanothin Descemet stripping automated endothelial keratoplasty performed on a lacerated cornea after globe rupture: a case report. BMC Ophthalmol 25(1):110, 2025.

  7. Igarashi S, Mandai M, Totani K, Yamanari M, Sakai D, Yamamoto M, Hirami Y, Sugiyama S, Kurimoto Y: Characterization of the depolarization contrast line in the outer retina using polarization-sensitive optical coherence tomography. Sci Rep 15(1):25394, 2025.

  8. Iwama Y, Sugase-Miyamoto Y, Onoue K, Uyama H, Matsuda K, Hayashi K, Akiba R, Masuda T, Yokota S, Yonemura S, Nishida K, Takahashi M, Kurimoto Y, Mandai M: Transplantation of human pluripotent stem cell-derived retinal sheet in a primate model of macular hole. Stem Cell Reports 19(11):1524-1533, 2024.

  9. Sakai D, Maeda T, Maeda A, Yamamoto M, Yokota S, Hirami Y, Nakamura M, Takahashi M, Mandai M, Kurimoto Y: Discrepancy between fundus autofluorescence abnormality and visual field loss in Bietti crystalline dystrophy. Retina 44(8):1394-1402, 2024.

  10. Hiraoka M, Urakawa Y, Kawai K, Yoshida A, Hosakawa J, Takazawa M, Inaba A, Yokota S, Hirami Y, Takahashi M, Ohara O, Kurimoto Y, Maeda A: Copy number variant detection using next-generation sequencing in EYS-associated retinitis pigmentosa. PLoS One 19(6):e0305812, 2024.

  11. Kajita K, Nishida M, Kurimoto Y, Yokota S, Sugita S, Semba T, Shirae S, Hayashi N, Ozaki A, Miura Y, Maeda A, Mitamura Y, Takahashi M, Mandai M: Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage. Sci Rep 14(1):10044, 2024.

  12. Sakai D, Maeda T, Yamamoto M, Yokota S, Maeda A, Hirami Y, Nakamura M, Kurimoto Y, Mandai M: Relationship between residual visual field and full-field stimulus testing in patients with late-stage retinal degenerative diseases. Sci Rep 14(1):2793, 2024.

  13. Kitahata S, Gocho K, Motozawa N, Yokota S, Yamamoto M, Maeda A, Hirami Y, Kurimoto Y, Kadonosono K, Takahashi M: Evaluation of photoreceptor features in retinitis pigmentosa with cystoid macular edema by using an adaptive optics fundus camera. PLoS One 19(1):e0296493, 2024.

  14. Hirami Y, Mandai M, Sugita S, Maeda A, Maeda T, Yamamoto M, Uyama H, Yokota S, Fujihara M, Igeta M, Daimon T, Fujita K, Ito T, Shibatani N, Morinaga C, Hayama T, Nakamura A, Ueyama K, Ono K, Ohara H, Fujiwara M, Yamasaki S, Watari K, Bando K, Kawabe K, Ikeda A, Kimura T, Kuwahara A, Takahashi M, Kurimoto Y: Safety and stable survival of stem-cell-derived retinal organoid for 2 years in patients with retinitis pigmentosa. Cell Stem Cell 30(12):–, 2023.

  15. Sakai D, Maeda T, Ozaki A, Kanda GN, Kurimoto Y, Takahashi M: Performance of ChatGPT in board examinations for specialists in the Japanese Ophthalmology Society. Cureus 15(12):e49903, 2023.

  16. Yamamoto M, Matsuyama T, Maeda T, Takagi S, Motozawa N, Sakai D, Hirami Y, Maeda A, Kurimoto Y, Takahashi M, Mandai M: Detailed evaluation of chromatic pupillometry and full-field stimulus testing to assess ultralow vision in retinitis pigmentosa. Ophthalmol Sci 3(4):100328, 2023.

  17. Sugita S, Usui Y, Watanabe H, Panto L, Iida M, Suginoshita K, Koyanagi KO, Nishida A, Kurimoto Y, Takahashi M, Shindo T, Nishioka H, Takano M, Kezuka T, Goto H, Kitaichi N: Adenovirus-associated uveitis with necrotizing retinitis. Ophthalmology 130(4):443-445, 2023.

  18. Sakai D, Hiraoka M, Matsuzaki M, Yokota S, Hirami Y, Onishi A, Nakamura M, Takahashi M, Kurimoto Y, Maeda A: Genotype and phenotype characteristics of RHO-associated retinitis pigmentosa in the Japanese population. Jpn J Ophthalmol 67(2):138-148, 2023.

  19. Sakai D, Yamamoto S, Yoshimizu S, Hirose F, Fujihara M, Nakamura M, Kurimoto Y: Ten-year outcomes of cataract surgery for glaucoma management in patients with primary angle-closure disease. Jpn J Ophthalmol 67(2):129-137, 2023.

  20. Uyama H, Tu HY, Sugita S, Yamasaki S, Kurimoto Y, Matsuyama T, Shiina T, Watanabe T, Takahashi M, Mandai M: Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates. Stem Cell Reports 17(11):2392-2408, 2022.

  21. Sakai D, Takagi S, Totani K, Yamamoto M, Matsuzaki M, Yamanari M, Sugiyama S, Yokota S, Maeda A, Hirami Y, Mandai M, Takahashi M, Nakamura M, Kurimoto Y: Retinal pigment epithelium melanin imaging using polarization-sensitive optical coherence tomography for patients with retinitis pigmentosa. Sci Rep 12:7115, 2022.

  22. Sakai D, Demoto S, Iwai Y, Hirami Y, Nakamura M, Kurimoto Y: Comparison of the Accuracy of Intraoperative Aberrometry in Intraocular Lens Implantation Between Myopic Eyes with Emmetropia and Myopia Targets. Clin Ophthalmol 16:1165-1171, 2022.

  23. Sakai D, Fujihara M, Yokota S, Nakamura M, Kurimoto Y: One-year outcomes and predictable factors for microhook ab interno trabeculotomy. Int J Ophthalmol 15:598-603, 2022.

  24. Sakai D, Takagi S, Hirami Y, Nakamura M, Kurimoto Y: Use of ellipsoid zone width for predicting visual prognosis after cataract surgery in patients with retinitis pigmentosa. Eye (Lond) 2022 Jan 1.

  25. Motozawa N, Miura T, Ochiai K, Yamamoto M, Horinouchi T, Tsuzuki T, Kanda GN, Ozawa Y, Tsujikawa A, Takahashi K, Takahashi M, Kurimoto Y, Maeda T, Mandai M: Automated evaluation of retinal pigment epithelium disease area in eyes with age-related macular degeneration. Sci Rep 12:892, 2022.

  26. Sakai D, Yokota S, Maeda A, Hirami Y, Nakamura M, Kurimoto Y: Ocular biometry with swept-source optical coherence tomography-based optical biometer in Japanese patients with EYS-related retinitis pigmentosa: a retrospective study. BMC Ophthalmol 22:51, 2022.

  27. Sakai D, Hirami Y, Nakamura M, Kurimoto Y: Accuracy of intraocular lens power calculation formulas in myopic eyes with target refractions of emmetropia and intentional myopia. Clin Ophthalmol 15:4535–4541, 2021.

  28. Tanaka F, Shibatani N, Fujita K, Ikesue H, Yoshimizu S, Muroi N, Kurimoto Y, Hashida T: Polypharmacy-associated potential contraindications of drug prescriptions in patients with primary angle closure disease in a real-world setting. J Pharm Health Care Sci 7:17, 2021.

  29. Sakai D, Takagi S, Hirami Y, Nakamura M, Kurimoto Y: Correlation between tangential distortion of the outer retinal layer and metamorphopsia in patients with epiretinal membrane. Graefes Arch Clin Exp Ophthalmol 259:1751-1758, 2021.

  30. Horiguchi H, Suzuki E, Kubo H, Fujikado T, Asonuma S, Fujimoto C, Tatsumoto M, Fukuchi T, Sakaue Y, Ichimura M, Kurimoto Y, Yamamoto M, Nakadomari S: Efficient measurements for the dynamic range of human lightness perception. Jpn J Ophthalmol 65:432-438, 2021.

  31. Yamanari M, Mase M, Obata R, Matsuzaki M, Minami T, Takagi S, Yamamoto M, Miyamoto N, Ueda K, Koide N, Maeda T, Totani K, Aoki N, Hirami Y, Sugiyama S, Mandai M, Aihara M, Takahashi M, Kato S, Kurimoto Y: Melanin concentration and depolarization metrics measurement by polarization-sensitive optical coherence tomography. Sci Rep 10:19513, 2020.

  32. Inaba A, Maeda A, Yoshida A, Kawai K, Hirami Y, Kurimoto Y, Kosugi S, Takahashi M: Truncating Variants Contribute to Hearing Loss and Severe Retinopathy in USH2A-Associated Retinitis Pigmentosa in Japanese Patients. Int J Mol Sci 21:7817, 2020.

  33. Sugita S, Mandai M, Hirami Y, Takagi S, Maeda T, Fujihara M, Matsuzaki M, Yamamoto M, Iseki K, Hayashi N, Hono A, Fujino S, Koide N, Sakai N, Shibata Y, Terada M, Nishida M, Dohi H, Nomura M, Amano N, Sakaguchi H, Hara C, Maruyama K, Daimon T, Igeta M, Oda T, Shirono U, Tozaki M, Totani K, Sugiyama S, Nishida K, Kurimoto Y, Takahashi M: HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration. J Clin Med 9:E2217, 2020.

  34. Matsuzaki M, Mandai M, Yamanari M, Totani K, Nishida M, Sugita S, Maeda T, Koide N, Takagi S, Hirami Y, Miyamoto N, Sugiyama S, Takahashi M, Kurimoto Y: Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium. Sci Rep 10:7656, 2020.

  35. An G, Akiba M, Yokota H, Motozawa N, Takagi S, Mandai M, Kitahata S, Hirami Y, Takahashi M, Kurimoto Y: Deep Learning Classification Models Built with Two-step Transfer Learning for Age Related Macular Degeneration Diagnosis. Conf Proc IEEE Eng Med Biol Soc 2019:2049-2052, 2019.

  36. Matsuzaki M, Ishii K, Nishida A, Motozawa N, Fujimori M, Hamada M, Kurimoto Y: Artifactual reduction in oxygen saturation readings affected by indocyanine green in ophthalmic angiography. Jpn J Ophthalmol 64:516-523, 2020.

  37. Fujii S, Sugita S, Futatsugi Y, Ishida M, Edo A, Makabe K, Kamao H, Iwasaki Y, Sakaguchi H, Hirami Y, Kurimoto Y, Takahashi M: A Strategy for Personalized Treatment of iPS-Retinal Immune Rejections Assessed in Cynomolgus Monkey Models. Int J Mol Sci 21:3077, 2020.

  38. Ito SI, Takagi S, Takahashi M, Sugita S, Hirami Y, Fujihara M, Uzu T, Azumi A, Kurimoto Y: Bilateral retinitis after influenza virus infection in a case report. Am J Ophthalmol Case Rep 17:100584, 2020.

  39. Motozawa N, An G, Takagi S, Kitahata S, Mandai M, Hirami Y, Yokota H, Akiba M, Tsujikawa A, Takahashi M, Kurimoto Y: Optical Coherence Tomography-Based Deep-Learning Models for Classifying Normal and Age-Related Macular Degeneration and Exudative and Non-Exudative Age-Related Macular Degeneration Changes. Ophthalmol Ther 8:527-539, 2019.

  40. Takagi S, Mandai M, Gocho K, Hirami Y, Yamamoto M, Fujihara M, Sugita S, Kurimoto Y, Takahashi M: Evaluation of Transplanted Autologous Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium in Exudative Age-Related Macular Degeneration. Ophthalmol Retina 3:850-859, 2019.

  41. Kubota F, Suetsugu T, Kato A, Gomi F, Takagi S, Kinoshita T, Ishikawa H, Mitamura Y, Kondo M, Iwahashi C, Kuwayama S, Kurimoto Y, Ogura Y, Yasukawa T; Japanese Clinical Retina Study (J-CREST) Group: Tilted Disc Syndrome Associated with Serous Retinal Detachment: Long-term Prognosis. A Retrospective Multicenter Survey. Am J Ophthalmol 207:313-318, 2019.

  42. Takagi S, Kudo S, Yokota H, Akiba M, Mandai M, Hirami Y, Takahashi M, Kurimoto Y, Ishida M: Assessment of the deformation of the outer nuclear layer in the Epiretinal membrane using spectral-domain optical coherence tomography. BMC Ophthalmol 19:113, 2019.

  43. Yoshimizu S, Hirose F, Takagi S, Fujihara M, Kurimoto Y: Comparison of pretreatment measurements of anterior segment parameters in eyes with acute and chronic primary angle closure. Jpn J Ophthalmol 63:151-157, 2019.

  44. Miyamoto N, Mandai M, Oishi A, Nakai S, Honda S, Hirashima T, Oh H, Matsumoto Y, Uenishi M, Kurimoto Y: Long-term results of photodynamic therapy or ranibizumab for polypoidal choroidal vasculopathy in LAPTOP study. Br J Ophthalmol 103:844-848, 2019.

  45. Takagi S, Mandai M, Hirami Y, Sugita S, Takahashi M, Kurimoto Y: Frequencies of human leukocyte antigen alleles and haplotypes among Japanese patients with age-related macular degeneration. Jpn J Ophthalmol 62:568-575, 2018.

  46. Maeda A, Yoshida A, Kawai K, Arai Y, Akiba R, Inaba A, Takagi S, Fujiki R, Hirami Y, Kurimoto Y, Ohara O, Takahashi M: Development of a molecular diagnostic test for Retinitis Pigmentosa in the Japanese population. Jpn J Ophthalmol 62:451-457, 2018.

  47. Takagi S, Hirami Y, Takahashi M, Fujihara M, Mandai M, Miyakoshi C, Tomita G, Kurimoto Y: Optical coherence tomography angiography in patients with retinitis pigmentosa who have normal visual acuity. Acta Ophthalmol 96:e636-e642, 2018.

  48. Kitahata S, Hirami Y, Takagi S, Kime C, Fujihara M, Kurimoto Y, Takahashi M: Efficacy of additional topical betamethasone in persistent cystoid macular oedema after carbonic anhydrase inhibitor treatments in retinitis pigmentosa. BMJ Open Ophthalmol 3:e000107, 2018.

  49. Matsuzaki M, Hirami Y, Uyama H, Kurimoto Y: Optical coherence tomography angiography changes in radial peripapillary capillaries in Leber hereditary optic neuropathy. Am J Ophthalmol Case Rep 9:51-55, 2018.

  50. Nakanishi H, Suda K, Yoshikawa M, Akagi T, Kameda T, Ikeda HO, Yokota S, Kurimoto Y, Tsujikawa A: Association of Bruch's membrane opening and optic disc morphology to axial length and visual field defects in eyes with primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 256:599-610, 2018.

  51. Takagi S, Hirami Y, Takahashi M, Yamamoto S, Goto S, Yamamoto M, Fujihara M, Tomita G, Kurimoto Y: Use of Wide-Field Fundus Camera, Fundus Autofluorescence, and OCT in Cases of Pigmented Paravenous Retinochoroidal Atrophy. Ophthalmol Retina 2:79-81, 2018.

  52. Motozawa N, Nakamura T, Takagi S, Fujihara M, Hirami Y, Ishida K, Sotozono C, Kurimoto Y: Unique circumferential peripheral keratitis in relapsing polychondritis. A case report. Medicine 96:e7951, 2017.

  53. Kawashima-Kumagai K, Yamashiro K, Yoshikawa M, Miyake M, Ming GCC, Fan Q, Koh JY, Saito M, Sugahara-Kuroda M, Oishi M, Akagi-Kurashige Y, Nakata I, Nakanishi H, Gotoh N, Oishi A, Tamura H, Ooto S, Tsujikawa A, Kurimoto Y, Sekiryu T, Matsuda F, Khor CC, Cheng CY, Wong TY, Yoshimura N: A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration. Sci Rep 7:7173, 2017.

  54. Mandai M, Kurimoto Y, Takahashi M: Autologous induced stem-cell-derived retinal cells for macular degeneration. N Engl J Med 377:792-793, 2017.

  55. Takagi S, Mandai M, Miyamoto N, Nishida A, Hirami Y, Uyama H, Yamamoto M, Takahashi M, Tomita G, Kurimoto Y: Incidence of outer retinal tubulation in eyes with choroidal neovascularization under intravitreal anti-vascular endothelial growth factor therapy in a Japanese population. Clin Ophthalmol 11:1219–1225, 2017.

  56. Miyamoto N, Mandai M, Kojima H, Kameda T, Shimozono M, Nishida A, Kurimoto Y: Response of eyes with age-related macular degeneration to anti-VEGF drugs and implications for therapy planning. Clin Ophthalmol 11:809-816, 2017.

  57. Miyamoto N, Ishida K, Kurimoto Y: Restoration of photoreceptor outer segments up to 24 months after pars plana vitrectomy in patients with diabetic macular edema. Ophthalmology Retina 1:389-394, 2017.

  58. Mandai M, Watanabe A, Kurimoto Y, Hirami Y, Morinaga C, Daimon T, Fujihara M, Akimaru H, Sakai N, Shibata Y, Terada M, Nomiya Y, Tanishima S, Nakamura M, Kamao H, Sugita S, Onishi A, Ito T, Fujita K, Kawamata S, Go MJ, Shinohara C, Hata KI, Sawada M, Yamamoto M, Ohta S, Ohara Y, Yoshida K, Kuwahara J, Kitano Y, Amano N, Umekage M, Kitaoka F, Tanaka A, Okada C, Takasu N, Ogawa S, Yamanaka S, Takahashi M: Autologous induced stem-cell-derived retinal cells for macular degeneration. N Engl J Med 376:1038-1046, 2017.

  59. Nishida A, Kojima H, Kameda T, Mandai M, Kurimoto Y: Five-year outcomes of pars plana vitrectomy for macular edema associated with branch retinal vein occlusion. Clin Ophthalmol 11:369-375, 2017.

  60. Kamao H, Mandai M, Ohashi W, Hirami Y, Kurimoto Y, Kiryu J, Takahashi M: Evaluation of the surgical device and procedure for extracellular Matrix-Scaffold-Supported human iPSC-Derived retinal pigment epithelium cell sheet transplantation. Invest Ophthalmol Vis Sci 58:211-220, 2017.

  61. Sugita S, Iwasaki Y, Makabe K, Kamao H, Mandai M, Shiina T, Ogasawara K, Hirami Y, Kurimoto Y, Takahashi M: Successful transplantation of retinal pigment epithelial cells from MHC homozygote iPSCs in MHC-matched models. Stem Cell Reports 17:635-648, 2016.

  62. Iraha S, Hirami Y, Ota S, Sunagawa GA, Mandai M, Tanihara H, Takahashi M, Kurimoto Y: Efficacy of valproic acid for retinitis pigmentosa patients: a pilot study. Clin Ophthalmol 10:1375-1384, 2016.

  63. Khor CC, Do T, Jia H, Nakano M, George R, Abu-Amero K, Duvesh R, Chen LJ, Li Z, Nongpiur ME, Perera SA, Qiao C, Wong HT, Sakai H, Barbosa de Melo M, Lee MC, Chan AS, Azhany Y, Dao TL, Ikeda Y, Perez-Grossmann RA, Zarnowski T, Day AC, Jonas JB, Tam PO, Tran TA, Ayub H, Akhtar F, Micheal S, Chew PT, Aljasim LA, Dada T, Luu TT, Awadalla MS, Kitnarong N, Wanichwecharungruang B, Aung YY, Mohamed-Noor J, Vijayan S, Sarangapani S, Husain R, Jap A, Baskaran M, Goh D, Su DH, Wang H, Yong VK, Yip LW, Trinh TB, Makornwattana M, Nguyen TT, Leuenberger EU, Park KH, Wiyogo WA, Kumar RS, Tello C, Kurimoto Y, Thapa SS, Pathanapitoon K, Salmon JF, Sohn YH, Fea A, Ozaki M, Lai JS, Tantisevi V, Khaing CC, Mizoguchi T, Nakano S, Kim CY, Tang G, Fan S, Wu R, Meng H, Nguyen TT, Tran TD, Ueno M, Martinez JM, Ramli N, Aung YM, Reyes RD, Vernon SA, Fang SK, Xie Z, Chen XY, Foo JN, Sim KS, Wong TT, Quek DT, Venkatesh R, Kavitha S, Krishnadas SR, Soumittra N, Shantha B, Lim BA, Ogle J, de Vasconcellos JP, Costa VP, Abe RY, de Souza BB, Sng CC, Aquino MC, Kosior-Jarecka E, Fong GB, Tamanaja VC, Fujita R, Jiang Y, Waseem N, Low S, Pham HN, Al-Shahwan S, Craven ER, Khan MI, Dada R, Mohanty K, Faiq MA, Hewitt AW, Burdon KP, Gan EH, Prutthipongsit A, Patthanathamrongkasem T, Catacutan MA, Felarca IR, Liao CS, Rusmayani E, Istiantoro VW, Consolandi G, Pignata G, Lavia C, Rojanapongpun P, Mangkornkanokpong L, Chansangpetch S, Chan JC, Choy BN, Shum JW, Than HM, Oo KT, Han AT, Yong VH, Ng XY, Goh SR, Chong YF, Hibberd ML, Seielstad M, Png E, Dunstan SJ, Chau NV, Bei J, Zeng YX, Karkey A, Basnyat B, Pasutto F, Paoli D, Frezzotti P, Wang JJ, Mitchell P, Fingert JH, Allingham RR, Hauser MA, Lim ST, Chew SH, Ebstein RP, Sakuntabhai A, Park KH, Ahn J, Boland G, Snippe H, Stead R, Quino R, Zaw SN, Lukasik U, Shetty R, Zahari M, Bae HW, Oo NL, Kubota T, Manassakorn A, Ho WL, Dallorto L, Hwang YH, Kiire CA, Kuroda M, Djamal ZE, Peregrino JI, Ghosh A, Jeoung JW, Hoan TS, Srisamran N, Sandragasu T, Set SH, Doan VH, Bhattacharya SS, Ho CL, Tan DT, Sihota R, Loon SC, Mori K, Kinoshita S, Hollander AI, Qamar R, Wang YX, Teo YY, Tai ES, Hartleben-Matkin C, Lozano-Giral D, Saw SM, Cheng CY, Zenteno JC, Pang CP, Bui HT, Hee O, Craig JE, Edward DP, Yonahara M, Neto JM, Guevara-Fujita ML, Xu L, Ritch R, Liza-Sharmini AT, Wong TY, Al-Obeidan S, Do NH, Sundaresan P, Tham CC, Foster PJ, Vijaya L, Tashiro K, Vithana EN, Wang N, Aung T: Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. Nat Genet 48:556-562, 2016.

  64. Yamada R, Hirose F, Matsuki T, Kameda T, Kurimoto Y: Comparison of mydriatic provocative and dark room prone provocative tests for anterior chamber angle configuration. J Glaucoma 25:482-486, 2016.

  65. Yamada R, Nishida A, Shimozono M, Kameda T, Miyamoto N, Mandai M, Kurimoto Y: Predictive factors for recurrence of macular edema after successful intravitreal bevacizumab therapy in branch retinal vein occlusion. Jpn J Ophthalmol 59:389-393, 2015.

  66. Akagi-Kurashige Y, Yamashiro K, Gotoh N, Miyake M, Morooka S, Yoshikawa M, Nakata I, Kumagai K, Tsujikawa A, Yamada R, Matsuda F, Saito M, Iida T, Sugahara M, Kurimoto Y, Cheng CY, Khor CC, Wong TY, Yoshimura N: MMP20 and ARMS2/HTRA1 are associated with neovascular lesion size in age-related macular degeneration. Ophthalmology 122:2295-2302, 2015.

  67. Miyake M, Yamashiro K, Tamura H, Kumagai K, Saito M, Sugahara-Kuroda M, Yoshikawa M, Oishi M, Akagi-Kurashige Y, Nakata I, Nakanishi H, Gotoh N, Oishi A, Matsuda F, Yamada R, Khor CC, Kurimoto Y, Sekiryu T, Tsujikawa A, Yoshimura N: The contribution of genetic architecture to the 10-year incidence of age-related macular degeneration in the fellow eye. Invest Ophthalmol Vis Sci 56:5353-5361, 2015.

  68. Arai Y, Maeda A, Hirami Y, Ishigami C, Kosugi S, Mandai M, Kurimoto Y, Takahashi M: Retinitis pigmentosa with EYS mutations is the most prevalent inherited retinal dystrophy in Japanese populations. J Ophthalmol 2015:819760, 2015.

  69. Cheng CY, Yamashiro K, Jia Chen L, Ahn J, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC: New loci and coding variants confer risk for age-related macular degeneration in East Asians. Nat Commun 6:6063, 2015.

  70. Matsuki T, Hirose F, Ito S, Hata M, Hirami Y, Kurimoto Y: Influence of anterior segment biometric parameters on the anterior chamber angle width in eyes with angle closure. J Glaucoma 24:144-148, 2015.

  71. Nongpiur M, Khor C, Jia H, Cornes B, Chen L, Qiao C, Nair K, Cheng C, Xu L, George R, Tan D, Abu-Amero K, Perera S, Ozaki M, Mizoguchi T, Kurimoto Y, Low S, Tajudin L, Ho CL, Tham C, Soto I, Chew P, Wong H, Shantha B, Kuroda M, Osman E, Tang G, Fan S, Meng H, Wang H, Feng B, Yong V, Ting S, Li Y, Wang Y, Li Z, Lavanya R, Wu R, Zheng Y, Su D, Loon S, Allingham R, Hauser M, Soumittra N, Ramprasad V, Waseem N, Yaakub A, Chia K, Kumaramanickavel G, Wong T, How A, Chau T, Simmons C, Bei JX, Zeng Y, Bhattacharya S, Zhang M, Tan D, Teo Y, Al-Obeidan S, Hon do N, Tai ES, Saw S, Foster P, Vijaya L, Jonas J, Wong T, John S, Pang C, Vithana E, Wang N, Aung T. ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma. PLoS Genet. 10(3):e1004089, 2014.

  72. Kuroda M, Hirami Y, Hata M, Mandai M, Takahashi M, Kurimoto Y. Intraretinal hyperreflective foci on spectral-domain optical coherence tomographic images of patients with retinitis pigmentosa. Clin Ophthalmol. 8:435–440, 2014.

  73. Oishi A, Miyamoto N, Mandai M, Honda S, Matsuoka T, Oh H, Kita M, Nagai T, Bessho N, Uenishi M, Kurimoto Y, Negi A. LAPTOP Study: A 24-Month Trial of Verteporfin Versus Ranibizumab for Polypoidal Choroidal Vasculopathy. Ophthalmology. 121:1151–1152, 2014.

  74. Fujita Y, Kinoshita M, Furukawa Y, Nagano T, Hashimoto H, Hirami Y, Kurimoto Y, Arakawa K, Yamazaki K, Okada Y, Katakami N, Uno E, Matsubara Y, Fukushima M, Nada A, Losordo DW, Asahara T, Okita Y, Kawamoto A. Phase II Clinical Trial of CD34+ Cell Therapy to Explore Endpoint Selection and Timing in Patients With Critical Limb Ischemia. Circ J. 78:490–501, 2014.

  75. Kuroda M, Nishida A, Kikuchi M, Kurimoto Y. Purtscher's retinopathy followed by neovascular glaucoma. Clin Ophthalmol. 7:2235–2237, 2013.

  76. Oishi A, Kojima H, Mandai M, Honda S, Matsuoka T, Oh H, Kita M, Nagai T, Fujihara M, Bessho N, Uenishi M, Kurimoto Y, Negi A. Comparison of the Effect of Ranibizumab and Verteporfin for Polypoidal Choroidal Vasculopathy: 12-Month LAPTOP Study Results. Am J Ophthalmol. 156:644–651, 2013.

  77. Hirose F, Hata M, Ito S, Matsuki T, Kurimoto Y. Light-dark changes in iris thickness and anterior chamber angle width in eyes with occludable angles. Graefes Arch Clin Exp Ophthalmol. 251:2395–2402, 2013.

  78. Miki A, Honda S, Kojima H, Nishizaki M, Nagai T, Fujihara M, Uenishi M, Kita M, Kurimoto Y, Negi A. Visual outcome of photodynamic therapy for typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy over 5 years of follow-up. Jpn J Ophthalmol. 57:301–307, 2013.

  79. Ito S, Miyamoto N, Ishida K, Kurimoto Y. Association between external limiting membrane status and visual acuity in diabetic macular edema. Br J Ophthalmol.97:228–232, 2013.

  80. Hata M, Oishi A, Shimozono M, Mandai M, Nishida A, Kurimoto Y. Early changes in foveal thickness in eyes with central serous chorioretinopathy. Retina. 33:296–301, 2013.

  81. Oishi A, Shimozono M, Mandai M, Hata M, Nishida A, Kurimoto Y. Recovery of photoreceptor outer segments after anti-VEGF therapy for age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 251:435–440, 2013.

  82. Hata M, Oishi A, Kurimoto Y. Unique optical coherence tomography findings in a case of macular retinitis caused by subacute sclerosing panencephalitis. Retin Cases Brief Rep. 6:435–437, 2012.

  83. Hata M, Hirose F, Oishi A, Hirami Y, Kurimoto Y. Changes in choroidal thickness and optical axial length accompanying intraocular pressure increase. Jpn J Ophthalmol.56:564–568, 2012.

  84. Hata M, Nakamura T, Sotozono C, Kumagai K, Kinoshita S, Kurimoto Y. Atypical Continuous Keratitis in a Case of Rheumatoid Arthritis Accompanying with Severe Scleritis. Cornea. 31:1493–1496, 2012.

  85. Shimozono M, Oishi A, Hata M, Matsuki T, Ito S, Ishida K, Kurimoto Y. The Significance of Cone Outer Segment Tips as a Prognostic Factor in Epiretinal Membrane Surgery. Am J Ophthalmol.153:698–704, 2012.

  86. Hata M, Oishi A, Mandai M, Kurimoto Y. Possible vitreous involvement in a case with rapidly progressing choroidal neovascularization. Indian J Ophthalmol.60:57–58, 2012.

  87. Kimakura M, Oishi A, Mandai M, Kurimoto Y. Bilateral Nonarteritic Anterior Ischemic Optic Neuropathy Following Intravitreal Injection of Pegaptanib. J Clin Exp Ophthalmol. 2:162, 2011.

  88. Hata M, Oishi A, Kurimoto Y, Yamamoto S, Kohara N. A Case of Posterior Reversible Encephalopathy Syndrome Presenting with Isolated Diplopia. J Clin Exp Ophthalmol.2:155, 2011.

  89. Oishi A, Mandai M, Kimakura M, Nishida A, Kurimoto Y. Characteristics of fine vascular network pattern associated with recurrence of polypoidal choroidal vasculopathy. Eye.25:1020–1026, 2011.

  90. Shimozono M, Oishi A, Hata M, Kurimoto Y. Restoration of the photoreceptor outer segment and visual outcomes after macular hole closure: spectral-domain optical coherence tomography analysis. Graefes Arch Clin Exp Ophthalmol. 249:1469–1476, 2011.

  91. Oishi A, Mandai M, Nishida A, Hata M, Matsuki T, Kurimoto Y. Remission and dropout rate of anti-VEGF therapy for age-related macular degeneration. Eur J Ophthalmol. 21:777–782, 2011.

  92. Nakata I, Yamashiro K, Yamada R, Gotoh N, Nakanishi H, Hayashi H, Tsujikawa A, Otani A, Ooto S, Tamura H, Saito M, Saito K, Iida T, Oishi A, Kurimoto Y, Matsuda F, Yoshimura N. Genetic Variants in Pigment Epithelium-Derived Factor Influence Response of Polypoidal Choroidal Vasculopathy to Photodynamic Therapy. Ophthalmology. 118:1408–1415, 2011.

  93. Shimozono M, Oishi A, Kimakura H, Kimakura M, Kurimoto Y. Three-step incision for 23-gauge vitrectomy reduces postoperative hypotony compared with an oblique incision. Ophthalmic Surg Lasers Imaging. 42:20–25, 2011.

  94. Nakanishi H, Yamashiro K, Yamada R, Gotoh N, Hayashi H, Nakata I, Saito M, Iida T, Oishi A, Kurimoto Y, Matsuo K, Tajima K, Matsuda F, Yoshimura N. Joint Effect of Cigarette Smoking and CFH and LOC387715/HTRA1 Polymorphisms on Polypoidal Choroidal Vasculopathy. Invest Ophthalmol Vis Sci. 51:6183–6187, 2010.

  95. Oishi A, Hata M, Shimozono M, Mandai M, Nishida A, Kurimoto Y. The significance of external limiting membrane status for visual acuity in age-related macular degeneration. Am J Ophthalmol. 150:27–32, 2010.

  96. Shimozono M, Uemura A, Hirami Y, Ishida K, Kurimoto Y. Corneal spherical aberration of eyes with cataract in a Japanese population. J Refract Surg. 26:457–459, 2010.

  97. Honda S, Kurimoto Y, Kagotani Y, Yamamoto H, Takagi H, Uenishi M; for the Hyogo Macular Disease Study Group. Photodynamic therapy for typical age-related macular degeneration and polypoidal choroidal vasculopathy: A 30-month multicenter study in Hyogo, Japan. Jpn J Ophthalmol. 53:593–597, 2009.

  98. Kawamoto A, Katayama M, Handa N, Kinoshita M, Takano H, Horii M, Sadamoto K, Yokoyama A, Yamanaka T, Onodera R, Kuroda A, Baba R, Kaneko Y, Tsukie T, Kurimoto Y, Okada Y, Kihara Y, Morioka S, Fukushima M, Asahara T. Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: a phase I/IIa, multicenter, single-blinded, dose-escalation clinical trial. Stem Cells. 27:2857–2864, 2009.

  99. Kumagai K, Oishi A, Fujihara M, Takahashi M, Kurimoto Y. Sub-Tenon’s injection of triamcinolone for optic disc neovascularization in a patient with retinitis pigmentosa. Jpn J Ophthalmol. 53:433–444, 2009.

  100. Honda S, Imai H, Yamashiro K, Kurimoto Y, Kanamori-Matsui N, Kagotani Y, Tamura Y, Yamamoto H, Ohoto S, Takagi H, Uenishi M, Negi A. Comparative Assessment of Photodynamic Therapy for Typical Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy: A Multicenter Study in Hyogo Prefecture, Japan. Ophthalmologica. 223:333–338, 2009.

  101. Nakanishi H, Kuriyama S, Saito I, Okada M, Kita M, Kurimoto Y, Kimura H, Takagi H, Yoshimura N. Prognostic factor analysis in pars plana vitrectomy for retinal detachment attributable to macular hole in high myopia: a multicenter study. Am J Ophthalmol. 2008;146:198-204.

  102. Yamashiro K, Tsujikawa A, Nishida A, Kurimoto Y. Determinants of Patient Satisfaction with Photodynamic Therapy for Neovascular Age-related Macular Degeneration or Polypoidal Choroidal Vasculopathy. Jpn J Ophthalmol. 2007;51:368-374.

  103. Nonaka A, Iwawaki T, Kikuchi M, Fujihara M, Nishida A, Kurimoto Y. Quantitative Evaluation of Iris Convexity in Primary Angle Closure. Am J Ophthalmol. 2007;143:695-697.

  104. Yu S, Tanabe T, Hangai M, Morishita S, Kurimoto Y, Yoshimura. Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in tilted disk. Am J Ophthalmol. 2006;142:475-482.

  105. Tsujikawa A, Kikuchi M, Ishida K, Nonaka A, Yamashiro K, Kurimoto Y. Fellow eye of patients with retinal detachment associated with macular hole and bilateral high myopia. Clin Experiment Ophthalmol. 2006;34:430-433.

  106. Tsujikawa A, Hangai M, Kikuchi M, Ishida K, Kurimoto Y. Visual Field Defect after Radial Optic Neurotomy for Central Retinal Vein Occlusion. Jpn J Ophthalmol. 2006;50:158-160.

  107. Nonaka A, Kondo T, Kikuchi M, Yamashiro K, Fujihara M, Iwawaki T, Yamamoto K, Kurimoto Y. Angle widening and alteration of ciliary process configuration after cataract surgery for primary angle closure. Ophthalmology. 2006;113:437-441.

  108. Fujihara M, Kikuchi M, Kurimoto Y. Methanol-induced retinal toxicity examined with optical coherence tomography. Jpn J Ophthalmol. 2006;50:239-241.

  109. Tsujikawa A. Fujiwara M, Iwawaki T, Yamamoto K, Kurimoto Y. Triamcinolone acetonide with vitrectomy for treatment of macular edema associated with branch retinal vein occlusion. Retina. 2005;25:861-867.

  110. Yamamoto K, Tsujikawa A, Hangai M, Fujihara M, Iwawaki T, Kurimoto Y. Neovascular glaucoma after branch retinal artery occlusion. Jpn J Ophthalmol. 2005;49:388-390.

  111. Tsujikawa A, Yamashiro K, Yamamoto K, Nonaka A, Fujihara M, Kurimoto Y. Retinal cystoid spaces in acute Vogt-Koyanagi-Harada syndrome. Am J Ophthalmol. 2005;139:670-677.

  112. Nonaka A, Kondo T, Kikuchi M, Yamashiro K, Fujihara M, Iwawaki T, Yamamoto K, Kurimoto Y. Cataract Surgery for Residual Angle closure after Peripheral Laser Iridotomy. Ophthalmology. 2005;112:974-979.

  113. Klassen HJ, Ng TF, Kurimoto Y, Kirov I, Shatos M, Coffey P, Young MJ. Multipotent retinal progenitors express developmental markers, differentiate into retinal neurons, and preserve light-mediated behavior. Invest Ophthalmol Vis Sci. 2004;45:4167-4173.

  114. Kaneko Y, Ichikawa M, Kurimoto Y, Ohta K, Yoshimura N. Neuronal Differentiation of Hippocampus-derived Neural Stem Cells Cultured in Conditioned Medium of Embryonic Rat Retina. Ophthalmic Res. 2003;35:268-275.

  115. Miyahara T, Kurimoto Y, Kurokawa T, Kuroda T, Yoshimura N. Alterations in Retinal Nerve Fiber Layer Thickness following Indirect Traumatic Optic Neuropathy Detected by Nerve Fiber Analyzer, GDx-N. Am J Ophthalmol. 2003;136:361-364.

  116. Gaun S, Kurimoto Y, Komurasaki Y, Yoshimura N. Vitreous surgery for bilateral bullous retinal detachment in Vogt-Koyanagi-Harada syndrome. Ophthalmic Surgery and Lasers. 2002;33:508-510.

  117. Lu B, Kwan T, Kurimoto Y, Shatos M, Lund R, Young, M. Transplantation of EGF-responsive neurospheres from GFP transgenic mice into the eyes of rd mice. Brain Res. 2002;943:292-300.

  118. Kurimoto Y, Shibuki H, Kaneko Y, Ichikawa M, Kurokawa T, Takahashi M, Yoshimura N. Transplantation of Adult Rat Hippocampus-derived Neural Stem Cells into Retina Injured by Transient Ischemia. Neurosci Lett. 2001;306:57-60.

  119. Kurimoto Y, Kaneko Y, Matsuno K, Akimoto M, Yoshimura N. Evaluation of the Retinal Nerve Fiber Layer Thickness in Eyes with Idiopathic Macular Holes. Am J Ophthalmol. 2001;131:756-760.

  120. Shatos MA, Mizumoto K, Mizumoto Y, Kurimoto Y, Klassen H, Young MJ. Multipotent stem cells from the brain and retina of green mice. e-biomed: The Journal of Regenerative Medicine. 2001;2:13-15.

  121. Matsuno K, Kurimoto Y, Umihira J, Hoya T, Yoshimura N. Comparative Study of Retinal Nerve Fiber Layer Loss in Normal-tension Glaucoma and Chronic Open-Angle Glaucoma. Ophthalmologica. 2001;215:108-112.

  122. Kurimoto Y, Matsuno K, Kaneko Y, Umihira J, Yoshimura N. Asymmetries of the retinal nerve fibre layer thickness. Br J Ophthalmol. 2000;84:469-472.

  123. Umihira J, Oguchi K, Kurimoto Y, Matsuno K, Fukasaku K, Yoshimura N. Optic nerve compression by internal carotid artery in the patients with normal-tension glaucoma. Br J Ophthalmol. 1999;83:1307-1308.

  124. Kurokawa T, Katai N, Kurimoto Y, Yoshimura N. BDNF suppresses expression of caspase-2 but not of c-Jun in retinal ganglion cells after ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 1999;40:3005-3011.

  125. Kurimoto Y, Komurasaki Y, Yoshimura N, Kondo T. Corneal astigmatism after cataract surgery with 4.1 mm BENT scleral and 4.1 mm plus meridian corneal incisions. J Cataract Refract Surg. 1999;25:427-431.

  126. Kurimoto Y, Park M, Sakaue H, Kondo T. Changes in the anterior chamber configuration after small-incision cataract surgery with posterior chamber intraocular lens implantation. Am J Ophthalmol. 1997;124:775-780.

  127. Kondo T, Miyazawa D, Unigame K, Kurimoto Y. Ultrasound biomicroscopic findings in humans with shallow anterior chamber and an increased intraocular pressure after the prone provocation test. Am J Ophthalmol. 1997;124:632-640.

  128. Kurimoto Y, Kawaguchi S, Murata M. Cerebellotectal projection in the rat: anterograde and retrograde WGA-HRP study of individual cerebellar nuclei. Neuroscience Research. 1995;22:57-71.

  129. Kawaguchi S, Murata M, Kurimoto Y. Ontogenesis of the cerebellofugal projection in the rat. Developmental Brain Research. 1991;61:285-289.

  130. Kawaguchi S, Murata M, Kurimoto Y. Ontogenesis and regeneration of the cerebellofugal projection in the rat. Biomedical Research. 1989;10(suppl 2):143-145.

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